{"title":"Metabolic Research","description":"\u003cp\u003ePeptides studied in the context of metabolic regulation, including glucose homeostasis, appetite signalling, lipid metabolism, and body composition research. For in vitro research use only.\u003c\/p\u003e","products":[{"product_id":"mots-c","title":"MOTS-C","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMOTS-c (Mitochondrial Open Reading Frame of 12S rRNA-c)\u003c\/strong\u003e is a 16-amino-acid mitochondria-derived peptide (MDP) encoded by a short open reading frame within the mitochondrial 12S rRNA gene. Discovered by Lee et al. in 2015, it represents a novel class of mitochondria-encoded hormones. MOTS-c is studied for its role in metabolic homeostasis, AMPK activation, insulin sensitivity, and adaptation to cellular stress.\u003c\/p\u003e\u003cp\u003eResearch has established MOTS-c as primarily acting on skeletal muscle, where it inhibits the folate cycle and de novo purine biosynthesis, leading to AMPK activation and improved metabolic signalling. In murine studies, MOTS-c treatment prevented age-dependent and high-fat-diet-induced insulin resistance and diet-induced obesity, positioning it as a key research target in metabolic disease, aging, and exercise biology.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 176489569  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C101H152N28O22S2  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e ~2,147 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Metabolic homeostasis · AMPK activation · Insulin sensitivity · Obesity models · Mitochondrial biology · Exercise physiology · Aging research\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSelected Research Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25738459\/\" target=\"_blank\" rel=\"noopener\"\u003eMOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance (PMID 25738459)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27216708\/\" target=\"_blank\" rel=\"noopener\"\u003eMOTS-c: a novel MDP regulating muscle and fat metabolism (PMID 27216708)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=MOTS-c+mitochondrial+derived+peptide+metabolism\" target=\"_blank\" rel=\"noopener\"\u003eFull PubMed literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"10mg","offer_id":53109143732557,"sku":null,"price":29.0,"currency_code":"GBP","in_stock":false},{"title":"40mg","offer_id":53109143765325,"sku":null,"price":58.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/MOTS-C40mgBox-M.jpg?v=1770812311"},{"product_id":"aod-9604","title":"AOD 9604","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAOD-9604\u003c\/strong\u003e is a synthetic peptide fragment corresponding to residues 177–191 of human growth hormone (hGH), with a tyrosine modification at the N-terminus. Unlike full-length hGH, AOD-9604 does not bind the IGF-1 receptor or stimulate IGF-1 production, making it a selective tool for studying fat metabolism pathways without the anabolic effects associated with hGH.\u003c\/p\u003e\u003cp\u003ePreclinical research has investigated AOD-9604 for its ability to stimulate lipolysis and inhibit lipogenesis in adipocyte models, with studies exploring β3-adrenergic receptor involvement. It has undergone Phase I–III clinical trials for metabolic disorders, providing a substantial safety and pharmacokinetic dataset useful for research context.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 221231-10-3  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e ~1817 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Lipolysis · Lipogenesis inhibition · Fat metabolism · β3-adrenergic signalling · hGH fragment pharmacology · Metabolic disease models\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=AOD-9604+growth+hormone+fragment+lipolysis+fat+metabolism\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: AOD-9604 research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"5mg","offer_id":53109156774221,"sku":null,"price":38.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/AOD96045mgBox-M.jpg?v=1770812277"},{"product_id":"cjc-1295-no-dac","title":"CJC 1295 NO DAC IPAMORELIN","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCJC-1295 (No DAC) + Ipamorelin\u003c\/strong\u003e is a research peptide combination pairing a GHRH analogue with a selective GHRP to produce synergistic growth hormone secretagogue activity. CJC-1295 (No DAC; CAS 863288-34-0) is a 30-amino-acid GHRH analogue studied for its ability to stimulate pulsatile GH release from pituitary somatotrophs without drug affinity complex (DAC) extension. Ipamorelin (CAS 170851-70-4) is a highly selective pentapeptide GHRP that acts on the ghrelin\/GHS-R1a receptor to potentiate GH secretion with minimal off-target effects on cortisol or prolactin.\u003c\/p\u003e\u003cp\u003eThe combination is studied in preclinical endocrinology research for its ability to model pulsatile GH physiology, investigate somatotroph function, and study downstream IGF-1 and metabolic signalling. The two compounds act via distinct but complementary receptor pathways (GHRH-R and GHS-R1a), making their combination a useful dual-agonist research tool.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCJC-1295 CAS:\u003c\/strong\u003e 863288-34-0  ·  \u003cstrong\u003eIpamorelin CAS:\u003c\/strong\u003e 170851-70-4  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC (each component)  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder blend  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Pulsatile GH release · GHRH-R \/ GHS-R1a dual agonism · Endocrine signalling · IGF-1 pathway · Pituitary somatotroph function · Metabolic research\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9849822\/\" target=\"_blank\" rel=\"noopener\"\u003eIpamorelin: first selective growth hormone secretagogue (PMID 9849822)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10496658\/\" target=\"_blank\" rel=\"noopener\"\u003ePK\/PD modelling of ipamorelin in human volunteers (PMID 10496658)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=CJC-1295+ipamorelin+growth+hormone+GHRH\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: CJC-1295 + Ipamorelin research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"10mg","offer_id":53109168570701,"sku":null,"price":45.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/CJC-1295NODA10mgBox-M.jpg?v=1770812241"},{"product_id":"tesamorelin","title":"Tesamorelin","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTesamorelin\u003c\/strong\u003e is a synthetic analogue of endogenous growth hormone-releasing hormone (GHRH), comprising the full 44-amino acid sequence of GHRH with a trans-3-hexenoic acid moiety conjugated to the N-terminus for enhanced metabolic stability. This modification extends its plasma half-life relative to native GHRH while preserving high-affinity binding to the GHRH receptor (GHRH-R).\u003c\/p\u003e\u003cp\u003eTesamorelin is a clinically validated compound (FDA-approved as Egrifta for HIV-associated lipodystrophy), providing an extensive pharmacological and pharmacokinetic dataset for research context. Preclinical research examines its role in pulsatile GH secretion, IGF-1 pathway modulation, lipid metabolism, and neuroendocrine function. Its high receptor selectivity makes it a valuable tool for GHRH-R pathway investigation.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 218949-48-5  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e ~5135.9 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e GHRH-R pharmacology · Pulsatile GH secretion · IGF-1 signalling · Lipid metabolism · Lipodystrophy models · Neuroendocrine function\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=tesamorelin+GHRH+growth+hormone+lipodystrophy\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: Tesamorelin research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"5mg","offer_id":53109185642829,"sku":null,"price":35.0,"currency_code":"GBP","in_stock":true},{"title":"8.88mg","offer_id":54162039734605,"sku":null,"price":47.5,"currency_code":"GBP","in_stock":true},{"title":"10mg","offer_id":53109185675597,"sku":null,"price":65.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/Tesamorelin5mgBox-M.jpg?v=1770812162"},{"product_id":"5-amino-1mq","title":"5-Amino 1MQ","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e5-Amino-1MQ\u003c\/strong\u003e (5-amino-1-methylquinolinium iodide; CAS 42464-96-0) is a selective, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) — an enzyme that methylates nicotinamide (vitamin B3) to produce 1-methylnicotinamide, thereby consuming SAM (S-adenosylmethionine) and depleting methyl group availability for epigenetic and metabolic processes. NNMT is highly expressed in adipose tissue, where its activity correlates with obesity, insulin resistance, and metabolic syndrome.\u003c\/p\u003e\u003cp\u003eBy inhibiting NNMT, 5-Amino-1MQ increases intracellular NAD⁺ precursor availability, restores methyl group balance, and has been shown in preclinical models to reduce adiposity and improve insulin sensitivity. It is studied as a research tool for NNMT biology, one-carbon metabolism, NAD⁺\/NADH homeostasis, and epigenetic methylation dynamics in metabolic disease models.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 42464-96-0  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C10H11IN2 (iodide salt)  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 286.1 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C, protected from light\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e NNMT inhibition · NAD⁺ metabolism · One-carbon metabolism · Epigenetic methylation · Adipogenesis · Metabolic disease models · SAM\/SAH ratio\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=5-amino-1MQ+NNMT+inhibitor+NAD+metabolism\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: 5-Amino-1MQ research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"5mg","offer_id":53109196587341,"sku":null,"price":21.0,"currency_code":"GBP","in_stock":false},{"title":"50mg","offer_id":53128323531085,"sku":null,"price":68.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/5AMINO1MQ5mgBox-M.jpg?v=1770812125"},{"product_id":"slu-pp-332","title":"SLU-PP 332","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSLU-PP-332\u003c\/strong\u003e is a potent pan-agonist of the estrogen-related receptor (ERR) family — ERRα, ERRβ, and ERRγ — developed at St Louis University as a selective chemical probe for ERR-mediated transcriptional programmes. It functions as an exercise mimetic by activating the same mitochondrial biogenesis and oxidative metabolism pathways induced by physical exercise, without requiring physical activity.\u003c\/p\u003e\u003cp\u003eMechanistically, SLU-PP-332 drives ERR-dependent transcription of genes involved in fatty acid oxidation, OXPHOS complex assembly, and mitochondrial fusion dynamics. In rodent studies, it has been shown to increase aerobic exercise capacity and activate skeletal muscle fibre type switching. Its selectivity for ERRα\/β\/γ over classical oestrogen receptors (ERα\/β) makes it a valuable tool for dissecting ERR-specific biology.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 5338394  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C18H14N2O2  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 294.3 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e ERRα\/β\/γ agonism · Mitochondrial biogenesis · Oxidative metabolism · Exercise mimetic pharmacology · Skeletal muscle biology · AMPK \/ OXPHOS signalling\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=SLU-PP-332+ERR+exercise+mimetic+mitochondria\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: SLU-PP-332 research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"5mg","offer_id":53425689198925,"sku":null,"price":45.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/SLU-PP3325mgBox-M.jpg?v=1770812052"},{"product_id":"adipotide","title":"Adipotide","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdipotide\u003c\/strong\u003e (CKGGRAKDC-GG-D(KLAKLAK)₂) is a chimeric pro-apoptotic peptide comprising two functional domains: a vascular-targeting domain (CKGGRAKDC) that binds to prohibitin-1 and annexin A2 on the surface of blood vessels feeding adipose tissue, and a cell-disrupting domain (D(KLAKLAK)₂) that induces mitochondrial apoptosis upon internalisation.\u003c\/p\u003e\u003cp\u003eOriginally developed for cancer vasculature targeting, Adipotide was repurposed as an adipose-selective pro-apoptotic agent. Preclinical studies in obese non-human primates demonstrated significant reduction in body mass and waist circumference through targeted elimination of fat-feeding vasculature, establishing it as a key research tool in adipose biology, angiogenesis targeting, and metabolic disease research.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 163360068  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C111H206N36O28S2  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e ~2,700 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Adipose vascular targeting · Prohibitin \/ annexin A2 biology · Pro-apoptotic peptide design · Obesity \u0026amp; metabolic disease models · Angiogenesis research · Chimeric peptide pharmacology\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=adipotide+CKGGRAKDC+adipose+vascular+targeting+prohibitin\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: Adipotide research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"5mg","offer_id":53425623499085,"sku":null,"price":49.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/Adipotide-M.jpg?v=1772090778"},{"product_id":"ipamorelin","title":"Ipamorelin","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIpamorelin\u003c\/strong\u003e (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) is a synthetic pentapeptide and the first truly selective growth hormone secretagogue (GHS), developed as a tool to distinguish GHRP-mediated GH release from off-target ACTH, cortisol, and prolactin stimulation seen with earlier GHRPs such as GHRP-2 and GHRP-6. It acts as a potent, selective agonist at the ghrelin receptor (GHS-R1a).\u003c\/p\u003e\u003cp\u003eIpamorelin's exceptional GH-specificity makes it particularly valuable in research on the ghrelin\/GHS-R1a axis, pituitary somatotroph function, and GH\/IGF-1 pathway modulation without the confounding endocrine effects of less selective GHRPs. Pharmacokinetic studies in humans have characterised its dose-proportional GH stimulation profile, short half-life (~2 h), and clean endocrine selectivity profile.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 170851-70-4  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C38H49N9O5  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 711.9 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e GHS-R1a \/ ghrelin receptor pharmacology · Selective GH secretagogue · Pituitary somatotroph biology · GH\/IGF-1 pathway · Endocrine selectivity studies · Metabolic research\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSelected Research Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9849822\/\" target=\"_blank\" rel=\"noopener\"\u003eIpamorelin: the first selective growth hormone secretagogue (PMID 9849822)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10496658\/\" target=\"_blank\" rel=\"noopener\"\u003ePK\/PD modelling of ipamorelin in human volunteers (PMID 10496658)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19289567\/\" target=\"_blank\" rel=\"noopener\"\u003eIpamorelin as a novel ghrelin mimetic (PMID 19289567)\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"Default Title","offer_id":53425666195789,"sku":null,"price":35.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/Ipamorelin5mg-M.jpg?v=1772090649"},{"product_id":"l-carnitine","title":"L-Carnitine","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 10% automatically. Add 3+ to save 15%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eL-Carnitine\u003c\/strong\u003e ((R)-3-carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium) is a naturally occurring quaternary ammonium compound biosynthesised from lysine and methionine, found at high concentrations in cardiac and skeletal muscle. Its primary biochemical role is the transport of long-chain fatty acyl groups across the inner mitochondrial membrane via the carnitine shuttle system, enabling beta-oxidation and ATP production.\u003c\/p\u003e\u003cp\u003eIn laboratory research, L-Carnitine is studied as a cofactor in fatty acid oxidation assays, a modulator of the acyl-CoA\/CoA ratio, and an agent in mitochondrial energy metabolism studies. Research has also explored its role in oxidative stress reduction via removal of acyl groups that accumulate under metabolic stress conditions, and its potential in models of carnitine deficiency, insulin sensitivity, and exercise physiology.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 541-15-1  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C7H15NO3  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 161.2 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99%  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Solution (500 mg\/10 mL)  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e 2–8 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Mitochondrial fatty acid transport · Beta-oxidation · Carnitine shuttle system · Energy metabolism · Oxidative stress · Insulin sensitivity models\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=L-carnitine+mitochondria+fatty+acid+oxidation+metabolism\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: L-Carnitine research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"500mg\/10ml","offer_id":53425678385485,"sku":null,"price":25.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/L-Carnitine500mg10ml-M.jpg?v=1772090512"}],"url":"https:\/\/www.peptide-biosciences.com\/collections\/metabolic-research.oembed","provider":"Peptide Biosciences","version":"1.0","type":"link"}