{"title":"Mitochondrial \u0026 Cellular Senescence Research Peptides","description":"\u003cp\u003eCompounds used in laboratory research into mitochondrial function, telomere biology, oxidative stress and cellular senescence, including Epithalon, SS-31 (Elamipretide), MOTS-c and NAD+. Each batch is independently tested by HPLC and mass spectrometry, and its Certificate of Analysis is supplied with your order.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eSupplied as lyophilised powder for in vitro laboratory research only. Not for human or veterinary use.\u003c\/em\u003e\u003c\/p\u003e","products":[{"product_id":"ss31","title":"SS-31 (Elamipretide)","description":"\u003cp\u003e\u003cstrong\u003eSS-31 (Elamipretide)\u003c\/strong\u003e (D-Arg-2'6'-dimethylTyr-Lys-Phe-NH₂) is a mitochondria-targeting synthetic tetrapeptide with a unique alternating cationic-aromatic sequence that enables rapid, energy-independent accumulation at the inner mitochondrial membrane. It is studied for its role in cardiolipin stabilisation, reactive oxygen species (ROS) reduction, and restoration of mitochondrial cristae architecture.\u003c\/p\u003e\u003cp\u003ePreclinical and early clinical research has investigated SS-31 across multiple models of mitochondrial dysfunction, including cardiac ischaemia-reperfusion injury, age-related mitochondrial decline, acute kidney injury, and neurodegenerative disease models. Its mechanism centres on cardiolipin interaction, which restores electron transport chain efficiency and reduces oxidative stress without altering mitochondrial membrane potential.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 736992-21-5  ·  \u003cstrong\u003eSequence:\u003c\/strong\u003e D-Arg-dmTyr-Lys-Phe-NH₂  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e ~639.8 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Cardiolipin stabilisation · Mitochondrial bioenergetics · ROS reduction · Cardiac ischaemia models · Renal protection · Age-related mitochondrial decline\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28487636\/\" target=\"_blank\" rel=\"noopener\"\u003eSS-31 ameliorates isoflurane-induced mitochondrial impairment (PMID 28487636)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=elamipretide+SS-31+mitochondria+cardiolipin\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: SS-31 \/ Elamipretide research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"50mg","offer_id":53108999913805,"sku":"SS31-50MG-VL","price":70.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/SS3110mgBox-M.jpg?v=1770812534"},{"product_id":"klow","title":"Klow Blend","description":"\u003cp\u003e\u003cstrong\u003eKLOW Blend\u003c\/strong\u003e is a four-component research peptide combination formulated for laboratory studies of cell migration, extracellular matrix biology and immune signalling. The blend comprises: \u003cstrong\u003eGHK-Cu\u003c\/strong\u003e (CAS 49557-75-7) — copper tripeptide studied for ECM remodelling and collagen synthesis; \u003cstrong\u003eTB-500\u003c\/strong\u003e — actin-sequestering Thymosin β4 fragment (parent CAS 107761-42-2) studied for cellular migration and angiogenesis; \u003cstrong\u003eBPC-157\u003c\/strong\u003e (CAS 137525-51-0) — gastric pentadecapeptide studied for angiogenesis and GI mucosal biology; and \u003cstrong\u003eKPV\u003c\/strong\u003e — alpha-MSH C-terminal tripeptide studied for MC1R-mediated inflammatory signalling.\u003c\/p\u003e\u003cp\u003eThe combination covers complementary pathways: angiogenic (TB-500\/BPC-157), matrix remodelling (GHK-Cu), and immunomodulatory (KPV), for multi-target laboratory research on skin biology and inflammatory signalling.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eComponents:\u003c\/strong\u003e GHK-Cu · TB-500 · BPC-157 · KPV  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC (each component)  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder blend  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Multi-target pathway studies · ECM remodelling · Inflammatory signalling · Angiogenesis · Cellular migration · Skin biology\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25995620\/\" target=\"_blank\" rel=\"noopener\"\u003eBPC-157: wound healing and angiogenesis in vivo (PMID 25995620)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35083444\/\" target=\"_blank\" rel=\"noopener\"\u003eGHK-Cu as anti-aging peptide (PMID 35083444)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10469335\/\" target=\"_blank\" rel=\"noopener\"\u003eThymosin beta4 accelerates wound healing (PMID 10469335)\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"80mg \/ Vial","offer_id":53109161394509,"sku":"KLOW-80MG-VL","price":90.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/KLOW80mgBox-M.jpg?v=1770812498"},{"product_id":"ghk-cu","title":"GHK-Cu (Copper Peptide)","description":"\u003cp\u003e\u003cstrong\u003eGHK-Cu (Copper Tripeptide-1)\u003c\/strong\u003e (Gly-His-Lys·Cu²⁺; CAS 49557-75-7) is a naturally occurring copper peptide complex found in human plasma, saliva, and urine. Serum concentrations decline from approximately 200 ng\/mL at age 20 to 80 ng\/mL by age 60, making it a subject of interest in cellular senescence research. GHK-Cu is extensively studied for its role in extracellular matrix remodelling, collagen and glycosaminoglycan synthesis, and copper-dependent enzyme activity.\u003c\/p\u003e\u003cp\u003eGene-expression studies report that GHK-Cu modulates a broad set of extracellular-matrix genes and influences both collagen synthesis and metalloproteinase-regulated collagen turnover in dermal fibroblast models. Its antioxidant activity and effects on inflammatory signalling have been described in in vitro and preclinical studies.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 49557-75-7  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C14H24CuN6O4  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 403.9 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Collagen synthesis \u0026amp; ECM remodelling · Dermal fibroblast models · Inflammatory signalling · Hair follicle biology · Angiogenesis · Cellular senescence\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSelected Research Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35083444\/\" target=\"_blank\" rel=\"noopener\"\u003eGHK as an anti-aging peptide: mechanisms and potential (PMID 35083444)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26236730\/\" target=\"_blank\" rel=\"noopener\"\u003eGHK as modulator of multiple cellular pathways in skin regeneration (PMID 26236730)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23019153\/\" target=\"_blank\" rel=\"noopener\"\u003eStem cell recovering effect of copper-free GHK in skin (PMID 23019153)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=GHK-Cu+copper+tripeptide+wound+healing+collagen\" target=\"_blank\" rel=\"noopener\"\u003eFull PubMed literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"50mg \/ Vial","offer_id":53109106344269,"sku":"GHKCU-50MG-VL","price":35.0,"currency_code":"GBP","in_stock":true},{"title":"100mg \/ Vial","offer_id":53109106377037,"sku":"GHKCU-100MG-VL","price":60.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/GHK-CU50mgBox-M.jpg?v=1770812423"},{"product_id":"mots-c","title":"MOTS-C","description":"\u003cp\u003e\u003cstrong\u003eMOTS-c (Mitochondrial Open Reading Frame of 12S rRNA-c)\u003c\/strong\u003e is a 16-amino-acid mitochondria-derived peptide (MDP) encoded by a short open reading frame within the mitochondrial 12S rRNA gene. Discovered by Lee et al. in 2015, it represents a novel class of mitochondria-encoded hormones. MOTS-c is studied for its role in metabolic homeostasis, AMPK activation, insulin sensitivity, and adaptation to cellular stress.\u003c\/p\u003e\u003cp\u003eResearch has established MOTS-c as primarily acting on skeletal muscle, where it inhibits the folate cycle and de novo purine biosynthesis, leading to AMPK activation and improved metabolic signalling. Murine studies have examined its effects on insulin signalling and diet-induced metabolic changes, making it a research target in metabolic, ageing and exercise biology.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 176489569  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C101H152N28O22S2  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e ~2,147 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Metabolic homeostasis · AMPK activation · Insulin signalling · Metabolic disease models · Mitochondrial biology · Exercise physiology · Aging research\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSelected Research Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25738459\/\" target=\"_blank\" rel=\"noopener\"\u003eMOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance (PMID 25738459)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27216708\/\" target=\"_blank\" rel=\"noopener\"\u003eMOTS-c: a novel MDP regulating muscle and fat metabolism (PMID 27216708)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=MOTS-c+mitochondrial+derived+peptide+metabolism\" target=\"_blank\" rel=\"noopener\"\u003eFull PubMed literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"40mg \/ Vial","offer_id":53109143765325,"sku":"MOTS-40MG-VL","price":58.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/MOTS-C40mgBox-M.jpg?v=1770812311"},{"product_id":"nad","title":"NAD+","description":"\u003cp\u003e\u003cstrong\u003eNAD⁺ (Nicotinamide Adenine Dinucleotide)\u003c\/strong\u003e (CAS 53-84-9) is a fundamental coenzyme present in all living cells, functioning as an electron carrier in redox reactions and as a substrate for a broad class of enzymes including sirtuins (SIRT1–7), PARPs (poly ADP-ribose polymerases), and CD38. NAD⁺ levels decline with age and in conditions of metabolic stress, linking it to aging biology, DNA repair capacity, mitochondrial function, and circadian rhythm regulation.\u003c\/p\u003e\u003cp\u003eIn research settings, NAD⁺ is studied as a substrate for sirtuin-mediated deacetylation reactions, a regulator of PARP-1-dependent DNA damage responses, and a mediator of calcium signalling via CD38\/cADPR pathways. Supplementation studies have investigated its role in restoring mitochondrial function, improving insulin sensitivity, and modulating the aging transcriptome in model organisms.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 53-84-9  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C21H27N7O14P2  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 663.4 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98%  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Sirtuin substrate biology · PARP-1 \/ DNA repair · Mitochondrial bioenergetics · Aging \u0026amp; longevity research · Metabolic regulation · Circadian rhythm · CD38 signalling\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=NAD+nicotinamide+adenine+dinucleotide+sirtuin+aging+mitochondria\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: NAD⁺ research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"500mg \/ Vial","offer_id":53162478469453,"sku":"NAD-500MG-VL","price":100.0,"currency_code":"GBP","in_stock":true},{"title":"1000mg \/ Vial","offer_id":53162478502221,"sku":"NAD-1000MG-VL","price":175.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/NAD_500mgBox-M.jpg?v=1770812090"},{"product_id":"epithalon","title":"Epithalon (Epitalon)","description":"\u003cp\u003e\u003cstrong\u003eEpithalon (Epitalon)\u003c\/strong\u003e (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide analogue of Epithalamin, a polypeptide extract of the pineal gland. Developed by Vladimir Khavinson and colleagues at the Saint Petersburg Institute of Bioregulation and Gerontology, Epithalon is studied for its role in telomerase activation, telomere elongation, and cellular aging regulation.\u003c\/p\u003e\u003cp\u003eFoundational research has demonstrated that Epithalon can induce expression of the catalytic subunit of telomerase (hTERT) in human somatic cells that normally lack this activity, resulting in measurable telomere elongation and extended cell division capacity beyond the Hayflick limit. Animal studies have reported significant life span extension in rodent models. This makes it one of the most studied synthetic tetrapeptides in longevity and cellular aging research.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 307297-39-8  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C14H22N4O9  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 390.3 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Telomerase activation · Telomere elongation · Cellular senescence · Pineal gland biology · Longevity research · Hayflick limit models\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSelected Research Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12937682\/\" target=\"_blank\" rel=\"noopener\"\u003eEpithalon induces telomerase activity and telomere elongation in human somatic cells (PMID 12937682)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15455129\/\" target=\"_blank\" rel=\"noopener\"\u003eEpithalon promotes overcoming the Hayflick division limit (PMID 15455129)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14501183\/\" target=\"_blank\" rel=\"noopener\"\u003eEpitalon increases life span in SHR mice (PMID 14501183)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=epithalon+epitalon+telomerase+aging+telomere\" target=\"_blank\" rel=\"noopener\"\u003eFull PubMed literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"10mg \/ Vial","offer_id":53425648632141,"sku":"EPI-10MG-VL","price":25.0,"currency_code":"GBP","in_stock":false},{"title":"50mg \/ Vial","offer_id":53425648664909,"sku":"EPI-50MG-VL","price":65.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/Epithalon10mg-M.jpg?v=1772090686"},{"product_id":"snap-8","title":"Snap-8 (Acetyl Octapeptide-3)","description":"\u003cp\u003e\u003cstrong\u003eSnap-8 (Acetyl Octapeptide-3)\u003c\/strong\u003e is a synthetic eight-amino-acid acetylated peptide studied for its ability to inhibit SNARE complex formation at the neuromuscular junction. It mimics the N-terminal domain of SNAP-25, one of the three SNARE proteins required for synaptic vesicle fusion, thereby competitively reducing acetylcholine release and attenuating muscle contraction in research models.\u003c\/p\u003e\u003cp\u003eAs a longer-chain analogue of acetyl hexapeptide-3 (Argireline), Snap-8 is studied for its improved potency in SNARE inhibition assays and its application in cosmetic and dermatological research focused on dynamic expression line mechanisms. It is a standard reference compound in research on neuromuscular junction pharmacology, SNARE complex biology, and topical peptide delivery.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 868844-74-0  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e ~1075 g\/mol  ·  \u003cstrong\u003ePurity:\u003c\/strong\u003e ≥99% HPLC  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e SNARE complex inhibition · Acetylcholine release modulation · Neuromuscular junction pharmacology · Cosmetic peptide research · SNAP-25 peptide biology · Topical delivery models\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=SNAP-8+SNARE+acetylcholine+acetyl+octapeptide+neuromuscular\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: Snap-8 research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"10mg \/ Single","offer_id":53425683890509,"sku":"SN8-10MG-X1","price":22.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/Snap-810mg-M_e97db155-c4e0-4489-8501-648449b7654a.jpg?v=1772090418"},{"product_id":"ghk-cu-snap-8-serum","title":"GHK-Cu + Snap-8 Serum (30ml)","description":"\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eGHK-Cu + Snap-8 Serum\u003c\/strong\u003e is a pre-formulated cosmetic research serum combining two mechanistically distinct peptides. \u003cstrong\u003eGHK-Cu\u003c\/strong\u003e (Gly-His-Lys·Cu²⁺; CAS 49557-75-7) is a naturally occurring copper tripeptide complex studied for extracellular matrix remodelling, collagen and elastin synthesis, and dermal fibroblast signalling. \u003cstrong\u003eSnap-8\u003c\/strong\u003e (Acetyl Octapeptide-3; CAS 868844-74-0) is a SNARE complex inhibitor studied for its ability to attenuate acetylcholine-mediated muscle contraction at the neuromuscular junction.\u003c\/p\u003e\u003cp\u003eTogether they allow two distinct mechanisms to be studied in one formulation: extracellular-matrix gene expression (GHK-Cu) and SNARE-complex inhibition (Snap-8). The combination is used in cosmetic peptide research as a model multi-mechanism topical formulation.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eGHK-Cu CAS:\u003c\/strong\u003e 49557-75-7  ·  \u003cstrong\u003eSnap-8 CAS:\u003c\/strong\u003e 868844-74-0  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Pre-formulated serum  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e 2–8 °C, protected from light\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e ECM remodelling · Collagen synthesis · SNARE complex inhibition · Neuromuscular junction pharmacology · Cosmetic peptide delivery · Skin senescence models\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35083444\/\" target=\"_blank\" rel=\"noopener\"\u003eGHK-Cu: potential as anti-aging peptide (PMID 35083444)\u003c\/a\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26236730\/\" target=\"_blank\" rel=\"noopener\"\u003eGHK as modulator of skin regeneration (PMID 26236730)\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro cosmetic and laboratory research. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"30ml Bottle","offer_id":54169829015885,"sku":"SRM-GHKSN8-30ML","price":35.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/A2B0A6BE-4B04-44C9-9D8C-2A6E9823B297.png?v=1782469232"},{"product_id":"nad-capsules","title":"NAD+ Capsules","description":"\u003cdiv class=\"product-ai-wellness-guide__section\"\u003e\n\u003cdiv class=\"product-ai-wellness-guide__items\"\u003e\n\u003cdiv class=\"product-ai-wellness-guide__item\"\u003e\n\u003ch4 class=\"product-ai-wellness-guide__item-title\"\u003e\u003cstrong\u003eWhat it's for\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp class=\"product-ai-wellness-guide__item-desc\"\u003eCellular energy support - Healthy ageing support\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__item\"\u003e\n\u003ch4 class=\"product-ai-wellness-guide__item-title\"\u003e\u003cstrong\u003eWho it may fit\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp class=\"product-ai-wellness-guide__item-desc\"\u003eAdults with busy lifestyles seeking convenient daily cellular energy cofactor support.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__item\"\u003e\n\u003ch4 class=\"product-ai-wellness-guide__item-title\"\u003e\u003cstrong\u003eKey actives per serving\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul class=\"product-ai-wellness-guide__item-list\"\u003e\n\u003cli\u003eNAD (Nicotinamide Adenine Dinucleotide):\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e500mg\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__item\"\u003e\n\u003ch4 class=\"product-ai-wellness-guide__item-title\"\u003e\u003cstrong\u003eHow to take\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp class=\"product-ai-wellness-guide__item-desc\"\u003eTake 2 capsules once daily with 8–12 oz of water; taking at the same time each day may support consistent routine.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__item\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__section\"\u003e\n\u003cdiv class=\"product-ai-wellness-guide__header\"\u003e\n\u003cdiv class=\"product-ai-wellness-guide__icon-wrapper\"\u003e\u003csvg class=\"product-ai-wellness-guide__icon\" width=\"24\" height=\"24\"\u003e\u003cuse\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__title-wrapper\"\u003e\n\u003ch3 class=\"product-ai-wellness-guide__title\"\u003eIngredients explained\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__items\"\u003e\n\u003cdiv class=\"product-ai-wellness-guide__item\"\u003e\n\u003ch4 class=\"product-ai-wellness-guide__item-title\"\u003e\u003cstrong\u003eNAD (Nicotinamide Adenine Dinucleotide)\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp class=\"product-ai-wellness-guide__item-desc\"\u003eNAD functions as a central coenzyme in cellular energy production and redox reactions, accepting and donating electrons to help convert nutrients into ATP.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-ai-wellness-guide__item\"\u003e\n\u003cp class=\"product-ai-wellness-guide__item-desc\"\u003e\u003cstrong\u003eCaution:\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eBest taken with water and consistent daily timing; if you are pregnant, nursing, on medication, or have a health condition, speak with a healthcare professional because NAD influences cellular metabolism.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Peptide Biosciences","offers":[{"title":"Default Title","offer_id":54710681239885,"sku":"NADC-60CAP","price":30.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/NAD_F.jpg?v=1783919868"},{"product_id":"glutathione","title":"Glutathione","description":"\u003cp\u003e\u003cstrong\u003eGlutathione (GSH)\u003c\/strong\u003e (γ-Glu-Cys-Gly; CAS 70-18-8) is a tripeptide present at millimolar concentrations in most mammalian cells. Its defining structural feature is the gamma peptide bond linking the glutamate side-chain carboxyl to cysteine, which renders it resistant to cleavage by standard intracellular peptidases. The free cysteine thiol is the reactive centre responsible for its redox chemistry.\u003c\/p\u003e\u003cp\u003eGlutathione is the principal intracellular redox buffer, cycling between its reduced (GSH) and oxidised disulfide (GSSG) forms. It is a standard reagent and reference compound in research on reactive oxygen species scavenging, glutathione peroxidase and glutathione S-transferase enzymology, xenobiotic conjugation and phase II detoxification, and the GSH\/GSSG ratio as a marker of cellular redox state. Biosynthesis proceeds via glutamate-cysteine ligase (the rate-limiting step) and glutathione synthetase, with regeneration from GSSG catalysed by NADPH-dependent glutathione reductase.\u003c\/p\u003e\u003cp style=\"font-size:0.875em;border:1px solid #dde6f0;padding:10px;border-radius:4px;\"\u003e\u003cstrong\u003eCAS:\u003c\/strong\u003e 70-18-8  ·  \u003cstrong\u003eFormula:\u003c\/strong\u003e C₁₀H₁₇N₃O₆S  ·  \u003cstrong\u003eMW:\u003c\/strong\u003e 307.32 g\/mol  ·  \u003cstrong\u003eFormat:\u003c\/strong\u003e Lyophilised powder  ·  \u003cstrong\u003eStorage:\u003c\/strong\u003e −20 °C, protected from light\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Areas:\u003c\/strong\u003e Cellular redox homeostasis · ROS scavenging · GSH\/GSSG ratio · Glutathione peroxidase \u0026amp; S-transferase enzymology · Xenobiotic conjugation · Oxidative stress models · Mitochondrial redox signalling\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResearch Literature:\u003c\/strong\u003e\u003cbr\u003e• \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=glutathione+GSH+GSSG+oxidative+stress+redox+homeostasis\" target=\"_blank\" rel=\"noopener\"\u003ePubMed: Glutathione research literature →\u003c\/a\u003e\u003c\/p\u003e\u003cp style=\"background:#eef4fb;border-left:3px solid #0b4a7c;padding:10px 14px;margin-bottom:1em;font-size:0.875em;\"\u003e\u003cstrong\u003eMulti-Buy Savings\u003c\/strong\u003e — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.\u003c\/p\u003e\u003cp style=\"background:#fff8e6;border-left:3px solid #e6a817;padding:10px 14px;font-size:0.8em;line-height:1.5;margin-top:1em;\"\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.\u003c\/p\u003e","brand":"Peptide Biosciences","offers":[{"title":"600mg","offer_id":54494740873549,"sku":null,"price":25.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/8846\/2669\/files\/Glutathione600mg.png?v=1788675683"}],"url":"https:\/\/www.peptide-biosciences.com\/collections\/mitochondrial-senescence-research-peptides.oembed","provider":"Peptide Biosciences","version":"1.0","type":"link"}