AOD 9604

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AOD-9604 is a synthetic peptide fragment corresponding to residues 177–191 of human growth hormone (hGH), with a tyrosine modification at the N-terminus. Unlike full-length hGH, AOD-9604 does not bind the IGF-1 receptor or stimulate IGF-1 production, making it a selective tool for studying fat metabolism pathways without the anabolic effects associated with hGH.

Preclinical research has investigated AOD-9604 for its ability to stimulate lipolysis and inhibit lipogenesis in adipocyte models, with studies exploring β3-adrenergic receptor involvement. It has undergone Phase I–III clinical trials for metabolic disorders, providing a substantial safety and pharmacokinetic dataset useful for research context.

CAS: 221231-10-3  ·  MW: ~1817 g/mol  ·  Purity: ≥99% HPLC  ·  Format: Lyophilised powder  ·  Storage: −20 °C

Research Areas: Lipolysis · Lipogenesis inhibition · Fat metabolism · β3-adrenergic signalling · hGH fragment pharmacology · Metabolic disease models

Research Literature:
• PubMed: AOD-9604 research literature →

Research Use Only. Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.