• Ara-290 Research Peptide - Peptide Biosciences UK
  • Ara-290 Certificate of Analysis - Peptide Biosciences UK
  • Ara-290 Certificate of Analysis, image 2 - Peptide Biosciences UK
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Ara-290

Ara-290
£24.95
£24.95
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  • For in vitro laboratory research use only

Certificate of Analysis · Ara-290

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Ara-290 Certificate of Analysis - Peptide Biosciences UK
Ara-290 Certificate of Analysis, image 2 - Peptide Biosciences UK
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ARA-290 (Cibinetide) is an 11-amino-acid linear peptide (Glp-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser; CAS 1208243-50-8) engineered from the aqueous face of helix B of erythropoietin (EPO). The sequence corresponds to a region of the EPO tertiary structure that is not involved in binding the classical homodimeric EPO receptor, allowing ARA-290 to engage the innate repair receptor (IRR) — a heteromeric complex of the EPO receptor and the β-common receptor (CD131) — without the erythropoietic activity of the parent hormone.

Because it dissociates tissue-protective signalling from haematopoietic signalling, ARA-290 is a widely used research tool for isolating IRR-mediated pathways. The research literature examines its role in models of neuropathic pain, small nerve fibre density, sarcoidosis-associated neuropathy, ischaemia-reperfusion injury, and inflammatory resolution, as well as its pharmacokinetic profile relative to full-length EPO.

Specifications

CAS1208243-50-8
FormulaC₅₁H₈₄N₁₆O₂₁
MW~1257.3 g/mol
Purity≥99% HPLC
FormatLyophilised powder
Storage−20 °C

Research areas

  • Innate repair receptor (EPOR/CD131) signalling
  • Non-erythropoietic EPO derivatives
  • Neuropathic pain models
  • Small nerve fibre density
  • Ischaemia-reperfusion injury
  • Inflammatory resolution

Research Use Only. Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.

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