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Peptide Biosciences

DSIP

DSIP

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DSIP (Delta Sleep-Inducing Peptide) (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) is a neuromodulatory nonapeptide first isolated from rabbit cerebral venous blood in 1974. It is studied for its role in circadian rhythm regulation, stress hormone modulation, and neurophysiological signalling related to sleep-wake cycles in preclinical research models.

DSIP has been explored for its ability to modulate ACTH, cortisol, and somatostatin release, its interaction with opiate receptor systems, and its putative role in normalising sleep architecture in animal models of disrupted circadian function. Its broad neuromodulatory profile makes it a useful research tool in sleep biology, neuroendocrinology, and stress physiology.

CAS: 62568-57-4  ·  Formula: C35H48N10O15  ·  MW: 848.8 g/mol  ·  Purity: ≥99% HPLC  ·  Format: Lyophilised powder  ·  Storage: −20 °C

Research Areas: Circadian rhythm · Delta wave sleep regulation · ACTH & cortisol modulation · Somatostatin interaction · Neuroendocrinology · Opiate receptor research

Research Literature:
PubMed: DSIP research literature →

Research Use Only. Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.

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