Buy KPV Research Peptide UK | 99%+ Purity | Anti-Inflammatory

KPV (Lys-Pro-Val; α-MSH residues 11–13) is the C-terminal tripeptide of alpha-melanocyte stimulating hormone (α-MSH). While short, KPV retains the principal anti-inflammatory bioactivity of the parent 13-residue peptide, acting primarily via MC1R-mediated pathways to suppress NF-κB activation and pro-inflammatory cytokine release (TNF-α, IL-1β, IL-6) in immune and epithelial cell models.

Research has demonstrated KPV's anti-inflammatory efficacy in models of colitis, skin inflammation, and wound healing. Its small molecular size, resistance to proteolysis (conferred by the C-terminal valine), and ability to modulate both innate immune and adaptive inflammatory responses make it a highly versatile research peptide. It has been explored for delivery via oral and topical routes in preclinical models.

Sequence: H-Lys-Pro-Val-OH (α-MSH 11–13) · MW: 341.4 g/mol · Purity: ≥99% HPLC · Format: Lyophilised powder · Storage: −20 °C

Research Areas: MC1R-mediated anti-inflammatory signalling · NF-κB suppression · Cytokine inhibition · Inflammatory bowel disease models · Wound healing · Skin inflammation

Research Literature:
• PubMed: KPV research literature →

Multi-Buy Savings — Add 2+ products to save 4% automatically. Add 3+ to save 6%. Applied at checkout.

Research Use Only. Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.