Buy Dermorphin Research Peptide UK | 99%+ Purity

Dermorphin (Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂) is a naturally occurring heptapeptide first isolated from the skin secretions of South American Phyllomedusa bicolor and Phyllomedusa sauvagei frogs. It was the first naturally occurring opioid peptide found to contain a D-amino acid residue (D-alanine at position 2), which confers exceptional μ-opioid receptor (MOR) selectivity and metabolic stability versus endogenous enkephalins and endorphins.

Dermorphin is among the most potent natural μ-opioid receptor agonists known, with binding affinity and potency several hundred times greater than morphine. In research, it is used as a selective μ-opioid receptor probe to study MOR pharmacology, opioid receptor structure-activity relationships, pain signalling pathways, and the role of D-amino acid incorporation in peptide biology.

CAS: 77614-16-5 · Formula: C40H54N8O11S · MW: 882.97 g/mol · Purity: ≥99% HPLC · Format: Lyophilised powder · Storage: −20 °C

Research Areas: μ-opioid receptor (MOR) pharmacology · Opioid receptor SAR · D-amino acid peptide biology · Pain signalling models · Endogenous opioid systems · Amphibian peptide chemistry

Research Literature:
• PubMed: Dermorphin research literature →

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Cartridge Configuration. All cartridge variants are supplied as a pre-mixed, water-based solution, fully enclosed within a sealed, single-use disposable cartridge assembly.

Research Use Only. Supplied strictly for in vitro laboratory research by qualified professionals. Not for human or veterinary administration. Not evaluated by the MHRA or FDA for therapeutic use. Researchers must comply with the Human Medicines Regulations 2012 and all applicable institutional guidelines. Peptide Biosciences accepts no liability for use outside a controlled research context.